Major Routes through Mexico
Before choosing your daily distances, read our driving guide to livestock, topes and other road hazards.
Choose a region below to find driving routes through Baja, the West Coast, the interior, the Gulf Coast and the Yucatán Peninsula. Before setting out, check our current road reports for dated updates and our required documents guide for trip planning.

The Baja Routes explore the Baja Peninsula from the USA Border. The Highways tend to be narrow but the experiences are BIG and glorious.
North/South
Highway 1 Tijuana to Cabo San Lucas
Highway 5 Mexicali to San Felipe
West/East
Highway 2 Tijuana to Playa Bagdad
Highway 3 Ensenada to Junction Highway 5

The West Coast routes lead from the USA border all the way down to Guatemala. This route includes beach resorts to small beach communities; large cities to medium Mexican towns.
North/South
Highways 15 and 15D – Nogales to Mexico City
Highway 200 Tepic to Guatemala Border

Sometimes called the heart of Mexico; the interior routes offer a variety of experiences. Culture abounds; traditional to modern. Cowboys to ballet. The variety of architecture is amazing; Pyramids, skyscrapers, simple adobe abodes.
North/South
Highway 8 – Sonoyta to Puerto Peñasco
Highway 15 & 15D – Tepic, Nayarit to Atlacomulco
Highway 45 – Ciudad Juarez to Morelia, Michoacán
Highway 57 – Piedras Negras to Mexico City
Highway 85 – Nuevo Laredo to Ciudad Victoria
Morelia to Lázaro Cárdenas – connecting roads via Pátzcuaro and Uruapan
Highway 95 – Mexico City to Acapulco, Guerrero
Highway 135 Tehuacan to Oaxaca, Oaxaca
East West
Highway 2 – San Luis Río Colorado, Sonora to Ciudad Juarez
Highway 40 – Mazatlan, Sinaloa to Reynosa
Highway 150 – Mexico City to Veracruz
Highway 190 – Oaxaca to Comitán

Often unexplored, the Gulf Coast Routes offer a variety of city experiences as well as interesting rural life. Drug violence has deterred many travelers from this area.
North/South
Highway 101, 180 – Matamoros to Cancun

The Yucatan routes explore this amazing peninsula. Here you can discover a wealth of ancient cultures, pyramids and cenotes. The Caribbean beaches and resorts are some of the world’s best. The Yucatan offers everything from butterflies to flamingos.
A unique culture and cuisine to explore.
Clockwise
Highway 180 Isla Aguada to Cancun
Highway 307 Cancun to Chetumal
Highway 186 – Chetumal to Escárcega
